Vitamin E Ester · Softgels, Premixes & Skin Care
Vitamin E acetate (DL-α-tocopheryl acetate) is the stable ester form of vitamin E used in softgels, multivitamins, skin care, food fortification and feed. Sourced by Chelora Pharmachem, Mumbai, as 98% oil or 50% CWS powder, and delivered across India with a batch COA and SDS.
How Buying Works
Send the quantity, form (98% oil or 50% CWS powder), grade (IP, BP, USP, EP or FCC), delivery city and target date. Quote CAS 7695-91-2 so there is no confusion.
Price, lead time and packing in one reply, with the specification, COA and SDS/MSDS for your QA team to review.
Samples can be arranged for QC testing, softgel or premix trials and vendor qualification before your commercial order.
Packed, labelled and sent with invoice, batch COA and transport documents. Repeat orders are planned with you.
Product Overview
Vitamin E Acetate (DL-α-tocopheryl acetate, all-rac-α-tocopheryl acetate; CAS 7695-91-2) is the acetic acid ester of synthetic α-tocopherol. It is a clear, colourless to yellowish, viscous oil that is practically insoluble in water and freely soluble in oils and ethanol. Capping the phenolic –OH of vitamin E as an acetate makes it far more stable to air and light than free tocopherol, which is why it is the workhorse vitamin E for softgels, tablets, creams and premixes.
In the body and, more slowly, in the skin, the ester is hydrolysed to release α-tocopherol, the active vitamin. That is why it is used as a vitamin E source in supplements, fortified foods and animal feed, and as a skin-conditioning ingredient in creams, lotions and hair oils. It is not an antioxidant for the product itself, because the active –OH group is blocked. It is also not suitable for inhalation products: it has been strongly linked to vaping-associated lung injury (EVALI).
As a chemical supplier in Mumbai, Chelora Pharmachem supplies vitamin E acetate as 98% oil and as 50% cold-water-soluble (CWS) powder, in pharmacopoeia, food and feed grades, to nutraceutical, pharma, cosmetic, food and feed manufacturers across India. Every supply comes with a batch-wise COA, SDS/MSDS and specification, from trial lots and samples to regular bulk orders planned with you. Softgel makers can also source pharma-grade gelatin from us for the capsule shell.
In Depth
Vitamin E acetate is a chromanol ring carrying three methyl groups, joined to a saturated 16-carbon phytyl tail, with the ring’s phenolic –OH esterified as an acetate. It has three chiral centres, so eight stereoisomers are possible. The synthetic ‘dl’ or all-rac product contains all eight in about equal amounts, while natural vitamin E is a single isomer, RRR.
Free α-tocopherol is an antioxidant: its –OH group gives up a hydrogen atom to stop oxidation, and in doing so it is consumed and darkens. Blocking that group as an acetate makes the ester stable in storage and processing, but not an antioxidant in the pack. Digestive and skin enzymes later split the ester, releasing α-tocopherol, which then acts as vitamin E.
Synthetic all-rac-α-tocopherol is made by condensing trimethylhydroquinone with isophytol under acid catalysis to build the chromane ring and side chain. The tocopherol is then acetylated, typically with acetic anhydride, and purified by distillation. Natural d-α-tocopheryl acetate starts instead from tocopherols recovered from vegetable oil refining, which are concentrated, converted to the alpha form and esterified.
The oil grade is filled directly into softgels, alone or blended with other oils, and the 50% CWS powder goes into tablets, hard capsules, sachets and dry premixes. Under the traditional convention, 1 mg of DL-α-tocopheryl acetate equals 1 IU of vitamin E; current US labelling counts about 455 mg of α-tocopherol per gram, because only the 2R isomers are counted.
Confirm the form and isomer first: synthetic dl (all-rac) or natural d (RRR), acetate or free tocopherol, oil or 50% powder. Then compare assay, identification, optical rotation (near zero for dl), acidity, related substances, elemental impurities and residual solvents. For the powder, also check the carrier, loss on drying and particle size. Ask for the COA and SDS of the actual batch.
Chelora Pharmachem supplies vitamin E acetate (CAS 7695-91-2) from its centralized sales office in Mumbai to nutraceutical, pharma, cosmetic, food and feed manufacturers across India. Share the form (oil or 50% powder), grade, quantity, packing and delivery location, and our team replies with price, lead time and documents, from trial lots to regular bulk supply.
Global Sourcing
Our focus is the Indian market. When local supply is short, or you need a specific origin, natural d-α grade or pharmacopoeia grade, our international sourcing desk brings vitamin E acetate oil and powder in from trusted producers abroad, and our Mumbai team handles import, documents and delivery to your plant.
Product Profile
The identifiers and properties purchase and QA teams ask for first. Batch values are always confirmed on the COA.
Identity
EC 231-710-0. Sold as DL-α-tocopheryl acetate or all-rac-α-tocopheryl acetate.
A chromane ring with an acetate ester and a long phytyl side chain.
Appearance
Colourless to yellowish oil, almost odourless. The 50% CWS form is a white to off-white powder.
Solubility
Practically insoluble in water. Freely soluble in acetone, anhydrous ethanol and fatty oils.
Technical Data
Reference data for Vitamin E Acetate, useful when writing a specification, checking an SDS or planning storage and transport.
| Property | Value |
|---|---|
| IUPAC name | 2,5,7,8-Tetramethyl-2-(4,8,12-trimethyltridecyl)-3,4-dihydro-2H-chromen-6-yl acetate |
| Synonyms | DL-α-Tocopheryl acetate, all-rac-α-tocopheryl acetate, tocopheryl acetate, vitamin E acetate |
| CAS number | 7695-91-2 (all-rac / DL); some suppliers also list 52225-20-4. Natural RRR (d-α) form: 58-95-7 |
| EC number | 231-710-0 |
| PubChem CID | 2117 |
| Molecular formula | C31H52O3 |
| Molar mass | 472.74 g/mol |
| Appearance | Clear, colourless to yellowish or greenish-yellow, viscous oily liquid; almost odourless |
| Melting point | Below about −20 °C; liquid at room temperature |
| Boiling point | About 224 °C at 0.3 mmHg; decomposes before boiling at atmospheric pressure |
| Density | About 0.96–0.98 g/cm³ at 20 °C |
| Refractive index | About 1.497 (nD20) |
| Optical rotation | −0.01° to +0.01° (racemic DL form) |
| Flash point | Above 200 °C (closed cup; values vary by source) |
| Solubility in water | Practically insoluble (below about 1 mg/L at 20 °C) |
| Other solvents | Freely soluble in acetone, anhydrous ethanol, methylene chloride and fatty oils |
| HS code | 2936.28 (vitamin E and its derivatives) |
| Transport | Generally not regulated as a dangerous good for road, sea or air; confirm with the batch SDS |
Literature values for reference. Supplied material is tested batch-wise and reported on the COA.
Applications
Most vitamin E acetate goes into supplements and fortified foods and feeds as a stable vitamin E source; the rest goes into skin-care and hair-care products.
The 98% oil is the standard fill for vitamin E softgels, alone or blended with other oils, and is used in combination softgels with omega-3 or other fat-soluble vitamins. Its stability to air and light helps the fill hold its labelled potency through shelf life.
Oil grade, IP/USP/EP
The 50% CWS powder carries vitamin E acetate on a starch-based carrier, so it flows, compresses and blends like a dry ingredient. It goes into multivitamin tablets, hard capsules, effervescent and sachet products, and vitamin–mineral premixes.
50% CWS powder
Used as a skin-conditioning ingredient in creams, lotions, serums, lip balms, sunscreens and hair oils, where it is labelled as tocopheryl acetate. Being an ester, it keeps better in the formula than free tocopherol, and it is partly converted to tocopherol in the skin.
Cosmetic ingredient
Nuts, seeds and vegetable oils are natural sources of vitamin E. Food manufacturers add vitamin E acetate, usually as the CWS powder, to fortify milk powders, infant and clinical nutrition, cereals, beverages and bars, working to the limits their food regulations set.
FCC / food grade
Poultry, cattle, swine and aquaculture feeds are supplemented with vitamin E, mostly as DL-α-tocopheryl acetate in feed-grade powder form, to support growth, immunity and fertility. It is added through vitamin premixes that feed mills blend into compound feed.
Feed grade
Quality & Compliance
Every supply is backed by the documents your QA, regulatory and stores teams expect.
COA, batch-wise
Tests, limits and results for the exact batch you receive, shared before dispatch.
SDS / MSDS
Hazards, safe handling, storage, transport and first-aid measures for Vitamin E Acetate.
Technical data
Typical properties and the specification we supply against, to match with your in-house spec.
On request
Additional documents for vendor approval and audits can be arranged on request.
Safety & Handling
A short summary for stores, production and EHS teams. It does not replace the Safety Data Sheet supplied with every batch.
Not classified as hazardous under GHS or the EU CLP Regulation in major supplier SDSs. Spilled oil makes floors very slippery. It must not be used in inhalation or vaping products: inhaled vitamin E acetate has been strongly linked to lung injury (EVALI). Check the SDS of the batch for the classification that applies.
Wear safety glasses and chemical-resistant gloves, and use a dust mask where the powder form can become airborne. Use general ventilation and follow good industrial hygiene.
Keep containers tightly closed in a cool, dry place, protected from light and heat, ideally under nitrogen once opened. Store away from strong oxidising agents and strong alkalis.
Vitamin E acetate has no UN number and is generally not regulated as a dangerous good for road, sea or air transport. Always check the transport section of the SDS supplied with the batch.
Soak up spilled oil with an inert absorbent, sweep up powder without raising dust, and collect it in closed containers for disposal. It is not readily biodegradable, so keep it out of drains, soil and water courses.
PAN India Delivery
From our centralized sales office in Mumbai, we supply Vitamin E Acetate to buyers in every major manufacturing cluster.
MumbaiMumbai, Thane, Navi Mumbai, Tarapur, Boisar, Pune and Aurangabad.
AhmedabadAhmedabad, Vadodara, Ankleshwar and Vapi.
HyderabadHyderabad and Visakhapatnam.
BaddiBaddi and Haridwar.
GoaPharma and chemical units across Goa.
BengaluruBengaluru and Chennai.
IndoreIndore, Pithampur and Sikkim.
Specification
A typical specification for pharmacopoeia-grade vitamin E acetate oil (IP / BP / USP / EP). Share your in-house or pharmacopoeia specification, or your CWS powder spec, and we quote against it.
The Chemistry
Made
Trimethylhydroquinone and isophytol are condensed with an acid catalyst to form all-rac-α-tocopherol. Acetylating its phenolic –OH, usually with acetic anhydride, gives the acetate, which is distilled and then sold as oil or spray-dried onto a carrier as 50% powder.
Used
In the gut, and more slowly in the skin, esterases split off the acetate group and release α-tocopherol, the form the body uses. Until then the ester stays stable through softgel filling, tableting, premixing and pelleting, which is why formulators prefer it to free tocopherol.
Tested
Each batch is reported on a COA covering appearance, identification, GC assay, optical rotation, acidity, related substances, elemental impurities and residual solvents. The CWS powder COA adds loss on drying and particle size, so your QC team can release it quickly.
Stored
The ester resists oxidation far better than free tocopherol, but it is still sensitive to light and air over time. Keep drums closed, preferably under nitrogen, away from heat and sunlight, and keep the powder dry. Follow the SDS for handling.
Glossary
Terms you will meet on quotations, specifications and documents for Vitamin E Acetate.
FAQ
Anything else, call +91 98191 11179 or write to source@chelorapharmachem.com.
Request a QuoteVitamin E acetate (CAS 7695-91-2) is the stable form of vitamin E used in softgels, multivitamin tablets and premixes, fortified foods and beverages, and animal feed. It is also a skin-conditioning ingredient in creams, lotions, serums and hair oils, where it appears on labels as tocopheryl acetate.
The CAS number of DL-α-tocopheryl acetate (all-rac) is 7695-91-2, with EC number 231-710-0. Some suppliers and databases also list 52225-20-4 for the all-rac form. Natural d-α-tocopheryl acetate (RRR) has its own CAS number, 58-95-7, so state which one you need.
Usually, yes. In bulk trade, vitamin E acetate normally means synthetic DL-α-tocopheryl acetate, also called all-rac-α-tocopheryl acetate, CAS 7695-91-2. It is not the same as free tocopherol: the acetate ester is far more stable in storage and is converted to tocopherol in the body. Natural d-α-tocopheryl acetate also exists, so confirm the form on your enquiry.
Natural d-α (RRR) vitamin E is a single stereoisomer from vegetable oils. Synthetic dl-α (all-rac) is made chemically and contains eight stereoisomers in about equal amounts, only half of which (the 2R forms) the body retains well. So by weight, the synthetic form has roughly half to three-quarters of the activity of the natural form, depending on the convention used.
We supply 98% oil to IP, BP, USP and EP, 50% CWS powder for tablets and premixes, and food (FCC) and feed grades, subject to availability. Natural d-α-tocopheryl acetate can be sourced on request. Tell us the form, grade and carrier requirements when you enquire.
No. Vitamin E acetate was found in the lung fluid of 48 of 51 patients with vaping-associated lung injury (EVALI) in a CDC-led study published in 2020, and health authorities strongly linked it to the outbreak. We do not supply it for inhalation or vaping products.
Keep it in tightly closed containers in a cool, dry place, protected from light and heat, and away from strong oxidising agents and alkalis. Blanket opened drums of oil with nitrogen, and keep the powder dry. Follow the storage section of the SDS supplied with the batch.
Vitamin E acetate is generally classified under HS subheading 2936.28, which covers vitamin E and its derivatives. Powder forms on a carrier may be classified differently, so confirm the full national tariff code with your customs broker before import or export.
It is not classified as hazardous under GHS or the EU CLP Regulation in major supplier SDSs. Spilled oil is very slippery, the powder should not be breathed in as dust, and it must never be inhaled as a vapour. Read the SDS before handling.
No. Vitamin E acetate has no UN number and is generally not regulated as a dangerous good for road, sea or air transport. Always check the transport section of the SDS supplied with the batch.
We provide a batch-wise Certificate of Analysis (COA), SDS/MSDS and specifications. Additional documents for vendor qualification can be arranged on request.
Yes. We handle requirements from samples and trial lots for R&D, formulation and vendor approval up to regular bulk supply for commercial production, subject to product availability.
We supply buyers across India, including Maharashtra, Gujarat, Telangana, Andhra Pradesh, Himachal Pradesh, Goa, Karnataka, Tamil Nadu, Madhya Pradesh, Uttarakhand and Sikkim, from our centralized sales office in Mumbai.
Email source@chelorapharmachem.com or source@cheloragroup.com, call +91 98191 11179, or use the enquiry form on this page. Include the quantity, grade, delivery location and target date.
Request a Quote
Tell us the quantity, grade and delivery location. Our centralized sales team replies with competitive pricing, lead time and documentation.
