Vitamin B3 · Pharma, Cosmetic, Food & Feed Grades
Niacinamide (nicotinamide, CAS 98-92-0) is the amide form of vitamin B3, used in tablets, multivitamins, fortified foods, feed premixes and skin-care serums. Supplied by Chelora Pharmachem, Mumbai, and delivered across India with a batch COA and SDS.
How Buying Works
Send the quantity, grade (IP, BP, USP, EP, FCC, cosmetic or feed), delivery city and target date. Quote CAS 98-92-0 so there is no confusion.
Price, lead time and packing in one reply, with the specification, COA and SDS/MSDS for your QA team to review.
Samples can be arranged for QC testing, formulation and stability trials, and vendor qualification before your commercial order.
Packed, labelled and sent with invoice, batch COA and transport documents. Repeat orders are planned with you.
Product Overview
Niacinamide (nicotinamide, vitamin B3, pyridine-3-carboxamide; CAS 98-92-0) is the amide form of vitamin B3. It is a white crystalline powder or colourless crystals, very soluble in water and freely soluble in ethanol, with a melting range of 128–131 °C. In the body it is built into the coenzymes NAD and NADP, which is why it is used to prevent and treat niacin deficiency (pellagra) and appears in almost every B-complex and multivitamin formula.
Niacinamide is also one of the most widely used actives in skin care. Serums, moisturisers and sunscreens use it, typically at about 2–10%, to support the skin barrier and to target uneven tone, redness and oiliness. Food manufacturers add it to fortified flour, breakfast cereals and beverages, and feed manufacturers use it in vitamin premixes for poultry, pigs and cattle. Unlike nicotinic acid (niacin), it does not cause the skin flushing seen at higher doses, so it is the preferred form for most of these uses.
As a chemical supplier in Mumbai, Chelora Pharmachem supplies niacinamide in IP, BP, USP and EP pharmacopoeia grades, FCC food grade, cosmetic grade and feed grade to formulation, nutraceutical, cosmetic, food and feed manufacturers across India, with a batch-wise COA, SDS/MSDS and specification, from sample lots to regular bulk supply. Our team can also help you match the grade and physical form to your process. We also supply Folic Acid, another B vitamin used in tablets, premixes and food fortification.
In Depth
Niacinamide is a pyridine ring with a carboxamide group (–CONH₂) at the 3-position. The ring nitrogen is only weakly basic (pKa about 3.3), so a 5% solution in water is close to neutral, at pH 6.0–7.5. It is a small, polar, highly water-soluble molecule that is stable to heat and light in normal handling, which makes it easy to formulate.
In the body niacinamide is converted into NAD and NADP, coenzymes involved in hundreds of energy and repair reactions. That is its vitamin role. On the skin, it is used to support barrier lipids and reduce visible redness, oiliness and uneven tone. Under strong acid or alkali, and heat, the amide can hydrolyse to nicotinic acid, which formulators keep low.
Most commercial niacinamide starts from 3-methylpyridine (3-picoline). Ammoxidation with ammonia and air over a catalyst gives 3-cyanopyridine, which is then partially hydrolysed to the amide. Producers use either controlled chemical hydrolysis or a nitrile hydratase enzyme that stops at the amide instead of going on to nicotinic acid. The crude product is crystallised and dried to the required grade.
Niacinamide is the usual source of vitamin B3 in tablets, capsules, syrups and premixes because it is stable, very soluble and does not cause the flushing seen with nicotinic acid. It blends well with other B vitamins and minerals. Tablet makers often prefer granular or directly compressible forms, and premix makers often prefer free-flowing powder, so the physical form matters as much as the assay.
Confirm the grade first (IP, BP, USP, EP, FCC, cosmetic or feed), then compare assay, melting range, pH of solution, clarity and colour of solution, loss on drying, sulphated ash and related substances. Cosmetic buyers usually also ask for a low nicotinic acid content, while tablet and premix makers check particle size and flow. Ask for the COA and SDS of the actual batch.
Chelora Pharmachem supplies niacinamide (CAS 98-92-0) from its centralized sales office in Mumbai to formulation, nutraceutical, cosmetic, food and feed manufacturers across India. Share the grade, quantity, packing and delivery location, and our team replies with price, lead time and documents, from sample and trial lots to regular bulk supply, with imports arranged when local stock is short.
Global Sourcing
Our focus is the Indian market. When local supply is short, or you need a specific origin or grade, our international sourcing desk brings niacinamide in from trusted producers abroad, and our Mumbai team handles import, documents and delivery to your plant.
Product Profile
The identifiers and properties purchase and QA teams ask for first. Batch values are always confirmed on the COA.
Identity
EC 202-713-4. Also sold as nicotinamide, vitamin B3 or nicotinic acid amide.
A pyridine ring carrying a –CONH₂ amide group at the 3-position.
Appearance
White crystalline powder or colourless crystals. Odourless or almost odourless.
Solubility
Very soluble in water; about 1 g dissolves in 1.5 mL ethanol and in 10 mL glycerin.
Technical Data
Reference data for Niacinamide, useful when writing a specification, checking an SDS or planning storage and transport.
| Property | Value |
|---|---|
| IUPAC name | Pyridine-3-carboxamide |
| Synonyms | Niacinamide, nicotinamide, vitamin B3, nicotinic acid amide, 3-pyridinecarboxamide |
| CAS number | 98-92-0 |
| EC number | 202-713-4 |
| PubChem CID | 936 |
| Molecular formula | C6H6N2O |
| Molar mass | 122.13 g/mol |
| Appearance | White crystalline powder or colourless crystals |
| Odour | Odourless or almost odourless |
| Melting point | About 129 °C (pharmacopoeia range 128–131 °C) |
| Boiling point | About 334 °C (literature value); 150–160 °C under high vacuum |
| Density | About 1.40 g/cm³ at 25 °C |
| Solubility in water | Very soluble: about 1 g dissolves in 1 mL of water |
| Other solvents | Freely soluble in ethanol (about 1 g in 1.5 mL); soluble in glycerin (about 1 g in 10 mL) |
| pH | 6.0–7.5 (5% solution in water) |
| pKa | About 3.3 (pyridine nitrogen) |
| HS code | 2936.29 (Indian tariff item 2936 29 20) |
| Transport | Generally not regulated as a dangerous good for road, sea or air; confirm with the batch SDS |
Literature values for reference. Supplied material is tested batch-wise and reported on the COA.
Applications
Its main jobs are vitamin B3 in medicines and supplements and one of the best-known actives in skin care, with food fortification and animal feed close behind.
Niacinamide is the standard vitamin B3 source in B-complex and multivitamin tablets, capsules, syrups and effervescent products, and in medicines for niacin deficiency (pellagra). It is stable, very soluble and does not cause the flushing associated with nicotinic acid.
Pharma & nutraceutical
One of the most used actives in face serums, typically at about 2–10%, to support the skin barrier and help with uneven tone, redness, enlarged pores and oiliness. It is water-soluble, works at near-neutral pH and combines well with many other actives.
Cosmetic active
Moisturisers, body lotions, sunscreens, after-sun and hair-care products use niacinamide as a supporting active. Cosmetic-grade material with low nicotinic acid helps limit skin tingling, and its good solubility makes it easy to add to the water phase.
Personal care
Food-grade (FCC) niacinamide is added to fortified wheat flour and rice premixes, breakfast cereals, infant and clinical nutrition, health drinks and beverages to restore or add vitamin B3, usually dosed through a blended vitamin and mineral premix.
Food & beverage
Feed-grade niacinamide supplies vitamin B3 in vitamin and mineral premixes for poultry, pigs, cattle and aquaculture, supporting growth, feed conversion and general health. Premix makers usually look for a free-flowing powder that blends evenly with the other vitamins.
Feed additive
Quality & Compliance
Every supply is backed by the documents your QA, regulatory and stores teams expect.
COA, batch-wise
Tests, limits and results for the exact batch you receive, shared before dispatch.
SDS / MSDS
Hazards, safe handling, storage, transport and first-aid measures for Niacinamide.
Technical data
Typical properties and the specification we supply against, to match with your in-house spec.
On request
Additional documents for vendor approval and audits can be arranged on request.
Safety & Handling
A short summary for stores, production and EHS teams. It does not replace the Safety Data Sheet supplied with every batch.
No EU harmonised classification. The REACH registration and many supplier SDS classify it as causing serious eye irritation (Eye Irrit. 2), signal word Warning, while some SDS list it as not hazardous. Check the SDS of the batch for the classification that applies.
H319
Wear safety glasses with side shields, gloves and a dust mask where dust can form. Use local exhaust ventilation at charging and weighing points, wash hands after handling, and do not eat, drink or smoke in the work area.
Keep containers tightly closed in a cool, dry, well-ventilated store, protected from moisture and away from strong acids, strong bases and strong oxidising agents.
Like many organic powders, fine dust may form combustible concentrations in air, so avoid dust clouds and ignition sources. Niacinamide is generally not regulated as a dangerous good for road, sea or air transport.
Avoid raising dust, sweep or vacuum spilled material into closed containers for disposal, and keep it out of drains, soil and water courses.
PAN India Delivery
From our centralized sales office in Mumbai, we supply Niacinamide to buyers in every major manufacturing cluster.
MumbaiMumbai, Thane, Navi Mumbai, Tarapur, Boisar, Pune and Aurangabad.
AhmedabadAhmedabad, Vadodara, Ankleshwar and Vapi.
HyderabadHyderabad and Visakhapatnam.
BaddiBaddi and Haridwar.
GoaPharma and chemical units across Goa.
BengaluruBengaluru and Chennai.
IndoreIndore, Pithampur and Sikkim.
Specification
A typical specification for pharmacopoeia-grade niacinamide (IP / BP / USP / EP). Share your in-house, FCC, cosmetic or feed specification and we quote against it.
The Chemistry
Made
3-Methylpyridine is converted by ammoxidation into 3-cyanopyridine. Controlled hydrolysis, chemical or with a nitrile hydratase enzyme, adds one molecule of water to the nitrile group to give niacinamide, which is crystallised and dried to the grade required.
Used
Niacinamide is blended into vitamin tablets and capsules, dissolved into the water phase of serums and creams, and mixed into food and feed premixes. Its high water solubility and near-neutral pH make it one of the easier vitamins to formulate.
Tested
Each batch is reported on a COA covering appearance, identification, assay, melting range, pH, loss on drying, sulphated ash and related substances such as nicotinic acid, so your QC team can release it quickly against the pharmacopoeia you ordered.
Stored
Niacinamide is stable but takes up moisture from humid air, which can make the powder cake. Keep bags and drums tightly closed in a cool, dry store, away from strong acids, strong bases and strong oxidising agents, and follow the SDS for handling.
Glossary
Terms you will meet on quotations, specifications and documents for Niacinamide.
FAQ
Anything else, call +91 98191 11179 or write to source@chelorapharmachem.com.
Request a QuoteNiacinamide (CAS 98-92-0) is the vitamin B3 used in B-complex and multivitamin tablets, capsules and syrups, and in medicines for niacin deficiency. It is also a leading skin-care active in serums, creams and sunscreens, and is used in fortified flour, cereals and beverages and in animal feed premixes.
The CAS number is 98-92-0 and the EC number is 202-713-4. Its formula is C6H6N2O and its molar mass is 122.13 g/mol. Quoting the CAS number on your enquiry avoids confusion with nicotinic acid (niacin), which is CAS 59-67-6.
Yes. Niacinamide and nicotinamide are two names for the same substance, pyridine-3-carboxamide, CAS 98-92-0. It is one of the two forms of vitamin B3; the other is nicotinic acid (niacin).
Both are vitamin B3, but they are different chemicals. Niacin is nicotinic acid (pyridine-3-carboxylic acid, CAS 59-67-6); niacinamide is its amide (CAS 98-92-0). Niacin in high doses causes skin flushing, while niacinamide does not, which is why niacinamide is preferred in supplements and skin care. Order by CAS number to avoid mix-ups.
We supply pharmacopoeia grades to IP, BP, USP and EP, FCC food grade, cosmetic grade and feed grade, subject to availability. Tell us the grade, the application and any particle-size or nicotinic acid requirement when you enquire.
Many face serums and moisturisers use niacinamide at about 2–5%, and some serums go up to around 10%. The right level depends on the product, the other actives and the market’s rules, so formulators set it after their own stability and skin-compatibility testing.
Keep it in tightly closed containers in a cool, dry and well-ventilated store, protected from moisture and away from strong acids, strong bases and strong oxidising agents. Follow the storage section of the SDS supplied with the batch.
Niacinamide is generally classified under HS subheading 2936.29, other vitamins and their derivatives, unmixed. In the Indian tariff it falls under 2936 29 20, which covers nicotinic acid and nicotinamide. Confirm the full code with your customs broker before import or export.
It has low hazard. It has no EU harmonised classification, but the REACH registration and many supplier SDS classify it as causing serious eye irritation (H319), and fine dust can form combustible mixtures with air. Read the SDS before handling, and use eye protection, gloves and dust control.
Niacinamide is generally not regulated as a dangerous good for road, sea or air transport. Always check the transport section of the SDS supplied with the batch.
We provide a batch-wise Certificate of Analysis (COA), SDS/MSDS and specifications. Additional documents for vendor qualification can be arranged on request.
Yes. We handle requirements from samples and trial lots for R&D, formulation and vendor approval up to regular bulk supply for commercial production, subject to product availability.
We supply buyers across India, including Maharashtra, Gujarat, Telangana, Andhra Pradesh, Himachal Pradesh, Goa, Karnataka, Tamil Nadu, Madhya Pradesh, Uttarakhand and Sikkim, from our centralized sales office in Mumbai.
Email source@chelorapharmachem.com or source@cheloragroup.com, call +91 98191 11179, or use the enquiry form on this page. Include the quantity, grade, delivery location and target date.
Request a Quote
Tell us the quantity, grade and delivery location. Our centralized sales team replies with competitive pricing, lead time and documentation.
